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Only higher-dose tramadol outperforms placebo for improved pain, function in knee, hip OA

A daily 300 mg dose of tramadol — but not 100 or 200 mg doses — surpassed placebo in improving pain and function related to hip or knee osteoarthritis, but was linked to increasing adverse events, researchers noted in Arthritis Care & Research.

Source: Healio

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  • American Association of Hip and Knee Surgeons
  • American Academy of Orthopedic Surgeons
  • Alpha Omega Alpha Honor Medical Society
  • Sibley Memorial Hospital
  • Johns Hopkins University